The article reviews the use of partial least squares structural equation modeling (PLS-SEM) in management information systems (MIS) research published in this journal with a focus on the years 1992-2011. Data from an analysis of 65 empirical studies using the PLS-SEM technique in estimation models is discussed. The review found an increase in the use of PLS-SEM over time. Sample size, non-normal data, and formatively measured latent variables are given as reasons why PLS-SEM was selected as a research subject.